Rabbi Avraham, son of the sage Rabbi Yitzchak, son of the sage Rabbi Yechiel HaPisa, died in the year 5314 [(Sha'arei Kedusha 64b). And see there, and I received etc. (see year 5252)].

When Julius the Third was Pope, some apostates argued against certain aggadot of the Gemara, and they condemned them to burning. The Talmud was burned in Rome on Rosh Hashanah 5314, and in Bologna that same month, and in Romagna in Cheshvan, and in Ancona in Shevat, and so in all of Italy that year [(Sha'arei Kedusha 117b)].